Abib Rice Probiotics Overnight Mask Barrier Jelly | Unbiased Skincare Efficacy Review by AI

Review

Does Abib Rice Probiotics Overnight Mask Barrier Jelly Work?

According to CreamScan AI's analysis of the ingredient list, here’s what Abib Rice Probiotics Overnight Mask Barrier Jelly has to offer:

Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 4.6 out of 10.

Key Benefits of Abib Rice Probiotics Overnight Mask Barrier Jelly

These are the key benefits you can expect from using Abib Rice Probiotics Overnight Mask Barrier Jelly:

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Abib Rice Probiotics Overnight Mask Barrier Jelly is quite moisturizing, with a moisturizing rating of 4.6 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a very high humectancy of 9.2 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%) and Diglycerin (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Abib Rice Probiotics Overnight Mask Barrier Jelly

CreamScan AI identified a few things to consider before adding Abib Rice Probiotics Overnight Mask Barrier Jelly to your skincare routine:

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Abib Rice Probiotics Overnight Mask Barrier Jelly as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Abib Rice Probiotics Overnight Mask Barrier Jelly is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Adenosine, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Adenosine provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically exclude the possibility that Adenosine may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were accessible to the CreamScan team at the time of publication.

Therefore, this ingredient does not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Abib Rice Probiotics Overnight Mask Barrier Jelly

Here’s an overview of the pros and cons of Abib Rice Probiotics Overnight Mask Barrier Jelly to help you decide if it’s the right choice for your skincare routine:

Pros:

When used alone: Provides humectant-rich moisturizing ideal for oily skin
As part of a routine: A humectant moisturizing boost, beneficial for any skin type
Lightweight texture

Cons:

Needs to be paired with occlusives to seal in humectants if used as a standalone moisturizer

Questionable anti-wrinkle efficacy

Fragrance
Preservative
Formula helpers

Other

Est. % The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more	Ingredient	Origin	Functions
70	Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients. Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water.	Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
9	Dipropylene Glycol A clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products. Dipropylene Glycol A clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product. Formula helper Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product.
6	Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper Denaturant – turns alcohol undrinkable. Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product. Formula helper Denaturant – turns alcohol undrinkable. Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product.
4	Glyceryl Polymethacrylate A synthetic polymer that is typically used as a viscosity modifier. Its benefits include a light after-feel on the skin and soft film, which is why it is frequently used in serums. It can form transparent gels and suspend some oils and particulates. Glyceryl Polymethacrylate A synthetic polymer that is typically used as a viscosity modifier. Its benefits include a light after-feel on the skin and soft film, which is why it is frequently used in serums. It can form transparent gels and suspend some oils and particulates.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Film-forming – creates a film to increase wear time. Viscosity controlling – changes the thickness of a product. Formula helper Film-forming – creates a film to increase wear time. Viscosity controlling – changes the thickness of a product.
3	Lactobacillus/Rice Ferment Lactobacillus/Rice Ferment	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.
2.5	1,2-Hexanediol A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula. 1,2-Hexanediol A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Preservative, Preservatives prevent the growth of bacteria and fungi in a product. Preservative, Preservatives prevent the growth of bacteria and fungi in a product. Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
2	Diglycerin A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin. Diglycerin A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
1.5	Ammonium Acryloyldimethyltaurate/VP Copolymer A polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent. Ammonium Acryloyldimethyltaurate/VP Copolymer A polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Viscosity controlling – changes the thickness of a product. Formula helper Viscosity controlling – changes the thickness of a product.
1.3	Oryza Sativa (Rice) Bran Extract An extract from rice bran, the brown outer part of the rice kernel. It contains emollient fatty acids and antioxidants such as tocopherols (vitamin E) and γ-oryzanol. Oryza Sativa (Rice) Bran Extract An extract from rice bran, the brown outer part of the rice kernel. It contains emollient fatty acids and antioxidants such as tocopherols (vitamin E) and γ-oryzanol.	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials.	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Formula helper Chelating – deactivates harmful heavy metal ions. Formula helper Chelating – deactivates harmful heavy metal ions.
1	Acrylates/C10-30 Alkyl Acrylate Crosspolymer A synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products. Acrylates/C10-30 Alkyl Acrylate Crosspolymer A synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Emulsion stabilizing – increases the stability of a formula. Film-forming – creates a film to increase wear time. Viscosity controlling – changes the thickness of a product. Formula helper Emulsion stabilizing – increases the stability of a formula. Film-forming – creates a film to increase wear time. Viscosity controlling – changes the thickness of a product.
0.3	Tromethamine An ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level. Tromethamine An ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper pH adjuster – alters the pH level of a formula. Formula helper pH adjuster – alters the pH level of a formula.
0.3	Saccharomyces/Rice Bran Ferment Saccharomyces/Rice Bran Ferment	Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
0.3	Ethylhexylglycerin A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin. Ethylhexylglycerin A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product.
0.3	Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind. Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
0.3	Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties. Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.	Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging.
0.3	Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin. Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Exfoliant, Exfoliants remove dead skin cells from the surface of the skin via acid-based chemical reactions (e.g., AHA or BHA). Exfoliant, Exfoliants remove dead skin cells from the surface of the skin via acid-based chemical reactions (e.g., AHA or BHA). Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics.
0.3	Disodium EDTA A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions. Disodium EDTA A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Chelating – deactivates harmful heavy metal ions. Viscosity controlling – changes the thickness of a product. Formula helper Chelating – deactivates harmful heavy metal ions. Viscosity controlling – changes the thickness of a product.

Water

Function:

Origin:

Dipropylene Glycol

Function:

Origin:

Glycerin

Function:

Origin:

Glyceryl Polymethacrylate

Function:

Origin:

Lactobacillus/Rice Ferment

Function:

Origin:

2.5

1,2-Hexanediol

Function:

Origin:

Diglycerin

Function:

Origin:

1.5

Ammonium Acryloyldimethyltaurate/VP Copolymer

Function:

Origin:

1.3

Oryza Sativa (Rice) Bran Extract

Function:

Origin:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Function:

Origin:

0.3

Tromethamine

Function:

Origin:

0.3

Saccharomyces/Rice Bran Ferment

Function:

Origin:

0.3

Ethylhexylglycerin

Function:

Origin:

0.3

Adenosine

Function:

Origin:

0.3

Sodium Hyaluronate

Function:

Origin:

0.3

Allantoin

Function:

Origin:

0.3

Disodium EDTA

Function:

Origin:

Ratings

Glycerin

Diglycerin

Saccharomyces/Rice Bran Ferment

0.3

Ethylhexylglycerin

0.3

Sodium Hyaluronate

0.3

Allantoin

0.3

Benchmark

None

Benchmark

Moisturizing rating

4.6

Ingredient		Est. %	Benchmark Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity. Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity.	Raiting
Humectancy	All humectants	9.2	10	9.2
	Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	6
	Diglycerin A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin. Diglycerin A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin.	2
	Saccharomyces/Rice Bran Ferment Saccharomyces/Rice Bran Ferment	0.3
	Ethylhexylglycerin A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin. Ethylhexylglycerin A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.	0.3
	Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties. Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.	0.3
	Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin. Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.	0.3
Occlusivity	All occlusives	0.0	20	0.0
	None
Moisturizing rating				4.6

Ingredient	Est. %	Benchmark According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more. According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more.	Humectancy
Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	6
Diglycerin A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin. Diglycerin A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin.	2
Saccharomyces/Rice Bran Ferment Saccharomyces/Rice Bran Ferment	0.3
Ethylhexylglycerin A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin. Ethylhexylglycerin A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.	0.3
Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties. Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.	0.3
Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin. Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.	0.3
All humectants	9.2	10	9.2

Glycerin

Diglycerin

Saccharomyces/Rice Bran Ferment

0.3

Ethylhexylglycerin

0.3

Sodium Hyaluronate

0.3

Allantoin

0.3

Benchmark

Ingredient	Est. %	Benchmark The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled). The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled).	Occlusivity
None
All occlusives	0.0	20	0.0

None

Benchmark

Ingredient	Ingredient anti-wrinkle power Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account. Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account.	when present at, %	in this formula est. %	Rating
Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind. Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.	n/a This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient do not contribute to the anti-wrinkle rating. This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient do not contribute to the anti-wrinkle rating.	-	0.3	-
Total				0

Adenosine

Ingredient anti-wrinkle power

n/a

when present at, %

in this formula, est. %

0.3

Anti-wrinkle rating

Ingredient	Est. %	Benchmark It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants. It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants.	Rich in Antioxidants
Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties. Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.	0.3
All antioxidants	0.3	3	No

Sodium Hyaluronate

0.3

Benchmark

Ingredient	Est. %	Benchmark The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%. The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%.	Rich in Soothing
Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin. Allantoin A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.	0.3
All soothing	0.3	5	No

Allantoin

0.3

Benchmark

Ingredients explained

Water
Est. %	70
Function	Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water.

The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.

Dipropylene Glycol
Est. %	9
Function	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.

Glycerin
Est. %	6
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Denaturant, Denaturant – turns alcohol undrinkable. Denaturant, Denaturant – turns alcohol undrinkable. Solvent, Solvent – a liquid that dissolves other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Glyceryl Polymethacrylate
Est. %	4
Function	Film-Forming, Film-forming – creates a film to increase wear time. Film-Forming, Film-forming – creates a film to increase wear time. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A synthetic polymer that is typically used as a viscosity modifier. Its benefits include a light after-feel on the skin and soft film, which is why it is frequently used in serums. It can form transparent gels and suspend some oils and particulates.

Lactobacillus/Rice Ferment
Est. %	3
Function
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.

1,2-Hexanediol
Est. %	2.5
Function	Preservative, Preservatives prevent the growth of bacteria and fungi in a product. Preservative, Preservatives prevent the growth of bacteria and fungi in a product. Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.

Diglycerin
Est. %	2
Function	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin.

Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %	1.5
Function	Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.

Oryza Sativa (Rice) Bran Extract
Est. %	1.3
Function	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Chelating Chelating – deactivates harmful heavy metal ions. Chelating Chelating – deactivates harmful heavy metal ions.
Origin	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials.

An extract from rice bran, the brown outer part of the rice kernel. It contains emollient fatty acids and antioxidants such as tocopherols (vitamin E) and γ-oryzanol.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %	1
Function	Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Film-Forming, Film-forming – creates a film to increase wear time. Film-Forming, Film-forming – creates a film to increase wear time. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.

Tromethamine
Est. %	0.3
Function	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. pH Adjuster pH adjuster – alters the pH level of a formula. pH Adjuster pH adjuster – alters the pH level of a formula.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

An ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.

Saccharomyces/Rice Bran Ferment
Est. %	0.3
Function	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
Origin	Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.

Ethylhexylglycerin
Est. %	0.3
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.

Adenosine
Est. %	0.3
Function	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Sodium Hyaluronate
Est. %	0.3
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging.
Origin	Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Allantoin
Est. %	0.3
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Exfoliant, Exfoliants remove dead skin cells from the surface of the skin via acid-based chemical reactions (e.g., AHA or BHA). Exfoliant, Exfoliants remove dead skin cells from the surface of the skin via acid-based chemical reactions (e.g., AHA or BHA). Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.

Disodium EDTA
Est. %	0.3
Function	Chelating, Chelating – deactivates harmful heavy metal ions. Chelating, Chelating – deactivates harmful heavy metal ions. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.