A313 Cream with Retinol & Vitamin A | Unbiased Science-Based Efficacy Review

Review

Does A313 Cream with Retinol & Vitamin A Work?

Based on the ingredient list analysis by CreamScan AI, we could not confirm any moisturizing or anti-wrinkle benefits delivered by A313 Cream with Retinol & Vitamin A. However, you can explore the roles of specific ingredients in the Ingredients Explained section below.

Things to Be Aware Of: A313 Cream with Retinol & Vitamin A

CreamScan AI identified a few things to consider before adding A313 Cream with Retinol & Vitamin A to your skincare routine:

⚠️ Questionable anti-wrinkle efficacy

If one of your main reasons for choosing A313 Cream with Retinol & Vitamin A is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Retinyl Palmitate, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Retinyl Palmitate provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically rule out the possibility that Retinyl Palmitate may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.

Therefore, this ingredient does not generate the anti-wrinkle rating.

📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

Est. % The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more	Ingredient	Origin	Functions
63	PEG-400 PEG-400	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Binding – bonds ingredients together. Emulsion stabilizing – increases the stability of a formula. Solvent – a liquid that dissolves other ingredients. Formula helper Binding – bonds ingredients together. Emulsion stabilizing – increases the stability of a formula. Solvent – a liquid that dissolves other ingredients.
35	Polysorbate 80 A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities. Polysorbate 80 A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper Denaturant – turns alcohol undrinkable. Emulsifying – helps to mix water and oil together. Solubilizing – helps ingredients dissolve. Formula helper Denaturant – turns alcohol undrinkable. Emulsifying – helps to mix water and oil together. Solubilizing – helps ingredients dissolve.
2	Retinyl Palmitate An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects. Retinyl Palmitate An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.	Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.

PEG-400

Function:

Origin:

Polysorbate 80

Function:

Origin:

Retinyl Palmitate

Function:

Origin:

Ratings

None

Benchmark

None

Benchmark

Moisturizing rating

0.0

Ingredient		Est. %	Benchmark Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity. Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity.	Raiting
Humectancy	All humectants	0.0	10	0.0
	None
Occlusivity	All occlusives	0.0	20	0.0
	None
Moisturizing rating				0.0

Ingredient	Est. %	Benchmark According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more. According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more.	Humectancy
None
All humectants	0.0	10	0.0

None

Benchmark

Ingredient	Est. %	Benchmark The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled). The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled).	Occlusivity
None
All occlusives	0.0	20	0.0

None

Benchmark

Ingredient	Ingredient anti-wrinkle power Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account. Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account.	when present at, %	in this formula est. %	Rating
Retinyl Palmitate An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects. Retinyl Palmitate An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.	n/a This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient do not contribute to the anti-wrinkle rating. This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient do not contribute to the anti-wrinkle rating.	-	2	-
Total				0

Retinyl Palmitate

Ingredient anti-wrinkle power

n/a

when present at, %

in this formula, est. %

Anti-wrinkle rating

Ingredient	Est. %	Benchmark It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants. It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants.	Rich in Antioxidants
None
All antioxidants	0	3	No

None

Benchmark

Ingredient	Est. %	Benchmark The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%. The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%.	Rich in Soothing
None
All soothing	0	5	No

None

Benchmark

Ingredients explained

PEG-400
Est. %	63
Function	Binding, Binding – bonds ingredients together. Binding, Binding – bonds ingredients together. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

Polysorbate 80
Est. %	35
Function	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Denaturant, Denaturant – turns alcohol undrinkable. Denaturant, Denaturant – turns alcohol undrinkable. Emulsifying, Emulsifying – helps to mix water and oil together. Emulsifying, Emulsifying – helps to mix water and oil together. Solubilizing Solubilizing – helps ingredients dissolve. Solubilizing Solubilizing – helps ingredients dissolve.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.

Retinyl Palmitate
Est. %	2
Function	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
Origin	Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.