Neutrogena Healthy Skin Anti-Wrinkle Night Cream Review

Neutrogena Healthy Skin Anti-Wrinkle Night Cream
4.5
/ 10
Moisturizing
7.6 Humectancy icon Humectancy
1.4 Occlusivity icon Occlusivity
2.5Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does Neutrogena Healthy Skin Anti-Wrinkle Night Cream Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Neutrogena Healthy Skin Anti-Wrinkle Night Cream has to offer:
 
Moderate moisturizing. It has a moisturizing rating of 4.5 out of 10.
✅ Modest anti-wrinkle efficacy: Neutrogena Healthy Skin Anti-Wrinkle Night Cream has an anti-wrinkle rating of 2.5 out of 10 so you may expect some, although limited, effect on wrinkles.

  

Key Benefits of Neutrogena Healthy Skin Anti-Wrinkle Night Cream

 
These are the key benefits you can expect from using Neutrogena Healthy Skin Anti-Wrinkle Night Cream:
 

🔵 Lightweight Moisturizer Well-Suited for Oily Skin

According to CreamScan analysis, Neutrogena Healthy Skin Anti-Wrinkle Night Cream is quite moisturizing, with a moisturizing rating of 4.5 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.4 out of 10 and a high humectancy of 7.6 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It can also be a good option for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Enhancement for Any Skincare Routine

But it’s not limited to oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Neutrogena Healthy Skin Anti-Wrinkle Night Cream has a modest level of anti-wrinkle efficacy, rated 2.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Retinol (est. ≈0.1%),
 the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Neutrogena Healthy Skin Anti-Wrinkle Night Cream

 
CreamScan AI identified a few things to consider before adding Neutrogena Healthy Skin Anti-Wrinkle Night Cream to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

❗️Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

Pros & Cons of Neutrogena Healthy Skin Anti-Wrinkle Night Cream

 
Here’s an overview of the pros and cons of Neutrogena Healthy Skin Anti-Wrinkle Night Cream to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing well-suited for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to retinol
   

Summary: Neutrogena Healthy Skin Anti-Wrinkle Night Cream

 
Based on the ingredient list analysis, CreamScan AI suggests that Neutrogena Healthy Skin Anti-Wrinkle Night Cream
, when used alone, delivers lightweight, humectant-rich moisturizing that is well-suited for oily skin. As part of a moisturizing routine, it provides a humectant enhancement, beneficial for all skin types.
 
Neutrogena Healthy Skin Anti-Wrinkle Night Cream contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
That said, there are some things about Neutrogena Healthy Skin Anti-Wrinkle Night Cream worth noting.
 
This product contains retinol, the most powerful and well-researched non-prescription anti-wrinkle ingredient. However, retinol can make your skin more prone to sun damage and increase sensitivity, so it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
65
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.1
Est. %
Water
Function:
Origin:
C12-15 Alkyl Benzoate
Function:
Origin:
Glycerin
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Dimethicone
Function:
Origin:
Ethylhexyl Hydroxystearate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Panthenol
Function:
Origin:
Triethanolamine
Function:
Origin:
Butylene Glycol
Function:
Origin:
Carbomer
Function:
Origin:
Diazolidinyl Urea
Function:
Origin:
Cetearyl Glucoside
Function:
Origin:
Methylparaben
Function:
Origin:
Camellia Oleifera Leaf Extract
Function:
Origin:
BHT
Function:
Origin:
Propylparaben
Function:
Origin:
Disodium EDTA
Function:
Origin:
Tocopherol
Function:
Origin:
Polysorbate 20
Function:
Origin:
Retinol
Function:
Origin:

Ratings

All humectants
7.6
6
1.3
0.3
Benchmark
10
All occlusives
2.8
2.5
0.3
Benchmark
20
Moisturizing rating
4.5
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.6 10
7.6
6
1.3
0.3
Occlusivity All occlusives 2.8 20
1.4
2.5
0.3
Moisturizing rating
4.5
Ingredient Est. % Benchmark Humectancy
6
1.3
0.3
All humectants 7.6 10
7.6
All humectants
7.6
6
1.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2.5
0.3
All occlusives 2.8 20
1.4
All occlusives
2.8
2.5
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
Total
2.5
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Anti-wrinkle rating
2.5
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
0.3
0.3
0.3
All antioxidants 2.4 3 No
All antioxidants
2.4
Tocopheryl Acetate
1.5
Camellia Oleifera Leaf Extract
0.3
BHT
0.3
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.3
0.3
All soothing 1.6 5 No
All soothing
1.6
1.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
C12-15 Alkyl Benzoate
Est. %9
Function
Origin
C12-15 Alkyl BenzoateA synthetic emollient ester. It works to improve the appearance of the skin by filling in the microcracks on the surface, thereby making the skin appear softer and smoother. It imparts a lightweight, velvety feel.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Cetyl Alcohol
Est. %4
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Cetearyl Alcohol
Est. %3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Dimethicone
Est. %2.5
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Ethylhexyl Hydroxystearate
Est. %2
Function
Origin
Ethylhexyl Hydroxystearate
Tocopheryl Acetate
Est. %1.5
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Panthenol
Est. %1.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Triethanolamine
Est. %1
Function
Origin
TriethanolamineA clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Diazolidinyl Urea
Est. %0.3
Function
Origin
Diazolidinyl UreaA synthetic preservative that is effective against most common bacteria. It is not considered broad-spectrum because it does not act against any type of yeast or mold. It is therefore commonly paired with antifungal preservatives.
Cetearyl Glucoside
Est. %0.3
Function
Origin
Cetearyl GlucosideAn emulsifier that creates stable mixtures of oil in water that feel soft and spread easily. Cetearyl glucoside is sold with cetearyl alcohol as an emulsifier blend and also provides some body to the formula.
Methylparaben
Est. %0.3
Function
Origin
MethylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Camellia Oleifera Leaf Extract
Est. %0.3
Function
Origin
Camellia Oleifera Leaf ExtractAn emollient extract derived from the leaves of the Tea-oil Camellia, which is native to Southeast Asia. It contains astringent and wound-healing tannins that create a tightening feeling on the skin and can speed up the healing process of small cuts.
BHT
Est. %0.3
Function
Origin
BHTAn antioxidant ingredient that naturally occurs in green algae and some bacteria or fungi but, for commercial use, is created synthetically. BHT is also used occasionally as a fragrance, where it presents a sweet, camphor-like odor.
Propylparaben
Est. %0.3
Function
Origin
PropylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.