Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 Review

Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45
2.9
/ 10
Moisturizing
3.8 Humectancy icon Humectancy
2.0 Occlusivity icon Occlusivity
2.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
45
SPF icon
SPF
Review

Does Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 has to offer:
 
✅ Light moisturizing. It has a moisturizing rating of 2.9 out of 10.
✅ Modest anti-wrinkle efficacy: Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 has an anti-wrinkle rating of 2.5 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection
✅ High sun protection for extended outdoor activities and exposure.

  

Key Benefits of Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45

 
These are the key benefits you can expect from using Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45:
 

🔵 Basic Moisturizer for Combination and Oily Skin

According to CreamScan analysis, Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 is lightly moisturizing, with a moisturizing rating of 2.9 out of 10.

Is it more humectant or occlusive? Rather humectant. It has a low occlusivity of 2.0 out of 10 and a moderate humectancy of 3.8 out of 10, primarily due to the high content of Propanediol (est. ≈2.0%).

This product, when used alone as a moisturizer, provides moderate hydration in a relatively lightweight, non-greasy formula. This could work for people with oily skin who need a basic level of hydration.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 has a modest level of anti-wrinkle efficacy, rated 2.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Ascorbic Acid (est. ≈22.0%),
 or Vitamin C, a popular ingredient, yet with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 20 participants (Humbert et al.). This study showed that a cream with a relatively high concentration of 5% ascorbic acid reduced the average wrinkle depth by 7% after 6 months of use, compared to a vehicle (the same formulation without ascorbic acid).
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 is rich (> 3%) in antioxidants, specifically Ascorbic Acid (est. ≈22.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

☀️☀️☀️ High Sun Protection for Extended Outdoor Activities and Exposure

With an SPF of 45, Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 provides high sun protection, making it ideal for prolonged outdoor activities such as hiking, gardening, sports, or spending time at the beach.

This level of SPF blocks up to 98% of UVB rays, significantly reducing the risk of sunburn. When formulated as broad-spectrum, it also protects against UVA rays, which penetrate deeper into the skin and contribute to premature aging, hyperpigmentation, and long-term damage.

This level of SPF is recommended for most skin types, including those with moderate sun sensitivity. For individuals with fair or very sensitive skin, or under intense sun exposure, a higher SPF of 50+ is advised.

❗️For optimal protection, choose products labeled broad-spectrum to ensure defense against both UVA rays, which contribute to skin aging and pigmentation, and UVB rays that cause sunburn.

It's important to apply sunscreen generously and reapply every two hours or after swimming or sweating to maintain effectiveness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45

 
Here’s an overview of the pros and cons of Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ Basic moisturizing that can work for combination and oily skin
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
Provides high sun protection, ideal for prolonged outdoor activities such as hiking or beach outings, and suitable for most skin types
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45

 
Based on the ingredient list analysis, CreamScan AI suggests that Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45
, as a moisturizer, provides basic, lightweight hydration, making it suitable for combination and oily skin.
 
Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
With an SPF of 45, Neocutis ReACTIVE+ Anti-Oxidant Serum + Broad-spectrum SPF 45 delivers high sun protection, well-suited for extended outdoor activities such as hiking or beach outings, and compatible with most skin types.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
50
22
11
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
Est. %
Cyclopentasiloxane
Function:
Origin:
Ascorbic Acid
Function:
Origin:
Polysilicone-11
Function:
Origin:
Ethylhexyl Hydroxystearate
Function:
Origin:
Cetyl PEG/PPG-10/1 Dimethicone
Function:
Origin:
Dimethicone
Function:
Origin:
Propanediol
Function:
Origin:
Glycerin
Function:
Origin:
Tocopherol
Function:
Origin:
Creatine
Function:
Origin:
Epigallocatechin Gallate
Function:
Origin:
Dimethylmethoxy Chromanol
Function:
Origin:
Propylene Carbonate
Function:
Origin:
Disteardimonium Hectorite
Function:
Origin:

Ratings

All humectants
3.8
2
1.5
0.3
Benchmark
10
All occlusives
4.0
3.0
1.0
Benchmark
20
Moisturizing rating
2.9
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 3.8 10
3.8
2
1.5
0.3
Occlusivity All occlusives 4.0 20
2.0
3.0
1.0
Moisturizing rating
2.9
Ingredient Est. % Benchmark Humectancy
2
1.5
0.3
All humectants 3.8 10
3.8
All humectants
3.8
2
1.5
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
3
1
All occlusives 4.0 20
2.0
All occlusives
4.0
3.0
1.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 5 22 2.5
Total
2.5
Ascorbic Acid
2.5
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
22
Anti-wrinkle rating
2.5
Ingredient Est. % Benchmark
Rich in Antioxidants
22
1
0.3
0.3
All antioxidants 23.6 3 Rich in antioxidants
All antioxidants
23.6
Ascorbic Acid
22
Tocopherol
1
Epigallocatechin Gallate
0.3
Dimethylmethoxy Chromanol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Cyclopentasiloxane
Est. %50
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Ascorbic Acid
Est. %22
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Polysilicone-11
Est. %11
Function
Origin
Polysilicone-11A synthetic rubber-like substance of the silicone family that has no color or distinct scent. These are large molecules that cannot penetrate the skin but instead create a thin silky film on the skin's surface.
Ethylhexyl Hydroxystearate
Est. %6
Function
Origin
Ethylhexyl Hydroxystearate
Cetyl PEG/PPG-10/1 Dimethicone
Est. %4
Function
Origin
Cetyl PEG/PPG-10/1 DimethiconeA silicone-based powerful emulsifier that helps to create lightweight and pleasant feeling lotions and creams.
Dimethicone
Est. %3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Propanediol
Est. %2
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Tocopherol
Est. %1
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Creatine
Est. %0.3
Function
Origin
CreatineAn amino acid-like compound that regulates cellular energy metabolism. It is used in skincare to moisturize and bind water to the skin and can also improve skin firmness when combined with folic acid.
Epigallocatechin Gallate
Est. %0.3
Function
Origin
Epigallocatechin GallateA bioactive compound isolated from green tea with numerous beneficial effects. It is an astringent and antioxidant and can help the skin to heal, reduce redness, and treat UV-induced damage.
Dimethylmethoxy Chromanol
Est. %0.3
Function
Origin
Dimethylmethoxy ChromanolA synthetic ingredient designed to work as an antioxidant.
Propylene Carbonate
Est. %0.3
Function
Origin
Propylene CarbonateA derivative of propylene glycol that is used most frequently as a solvent. Additionally, propylene carbonate serves as a viscosity controlling agent reducing the thickness of the products it is added to.
Disteardimonium Hectorite
Est. %0.3
Function
Origin
Disteardimonium HectoriteA clay ingredient that functions primarily as a viscosity controlling agent that thickens all types of formulas. Disteardimonium hectorite imparts a smooth, velvety feel, making it a luxurious addition to any formula.