Medik8 Oxy-R Peptides Review

Medik8 Oxy-R Peptides
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Review

Does Medik8 Oxy-R Peptides Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Medik8 Oxy-R Peptides has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Antioxidant protection.

Key Benefits of Medik8 Oxy-R Peptides

 
These are the key benefits you can expect from using Medik8 Oxy-R Peptides:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Medik8 Oxy-R Peptides is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%) and Gluconolactone (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Medik8 Oxy-R Peptides is rich (> 3%) in antioxidants, specifically Artocarpus Lakoocha Wood Extract (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Medik8 Oxy-R Peptides

 
CreamScan AI identified a few things to consider before adding Medik8 Oxy-R Peptides to your skincare routine:
 

If It’s an Exfoliator, It May Increase Skin Photosensitivity Due to Lactic Acid

This product contains lactic acid, a popular AHA known for its ability to gently exfoliate and brighten the skin. It works by removing dead skin cells, revealing new, more delicate skin that is more vulnerable to sun damage.

In smaller quantities, lactic acid is often used as a pH adjuster and may not significantly contribute to exfoliation. However, at higher concentrations, it functions as an effective exfoliant with benefits and risks similar to other AHAs. Products with AHAs, including lactic acid, may increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

If this product is designed for exfoliation, applying a broad-spectrum sunscreen with at least SPF 30 daily is essential to protect your skin. Always check the label or the manufacturer’s website for specific usage instructions.

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Medik8 Oxy-R Peptides as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Medik8 Oxy-R Peptides is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Gluconolactone, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Gluconolactone provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically exclude the possibility that Gluconolactone may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were accessible to the CreamScan team at the time of publication.

Therefore, this ingredient does not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Medik8 Oxy-R Peptides

 
Here’s an overview of the pros and cons of Medik8 Oxy-R Peptides to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
  • Questionable anti-wrinkle efficacy

Ingredients

Est. % Ingredient Origin Functions
80
6
4
3
2
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Artocarpus Lakoocha Wood Extract
Function:
Origin:
Gluconolactone
Function:
Origin:
Acetyl Glycyl Beta-Alanine
Function:
Origin:
Glycerin
Function:
Origin:
Lactic Acid
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Disodium EDTA
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Xanthan Gum
Function:
Origin:
Calcium Gluconate
Function:
Origin:
Sodium Metabisulfite
Function:
Origin:
Tetrapeptide-30
Function:
Origin:
Hydroxyresveratrol
Function:
Origin:

Ratings

All humectants
12.4
6
3
1.5
1.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.4 10
10.0
6
3
1.5
1.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
3
1.5
1.3
0.3
0.3
All humectants 12.4 10
10
All humectants
12.4
6
3
1.5
1.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 3 -
Total
0
Gluconolactone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
All antioxidants 4.6 3 Rich in antioxidants
All antioxidants
4.6
Artocarpus Lakoocha Wood Extract
4
Sodium Hyaluronate
0.3
Sodium Metabisulfite
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Artocarpus Lakoocha Wood Extract
Est. %4
Function
Origin
Artocarpus Lakoocha Wood Extract
Gluconolactone
Est. %3
Function
Origin
GluconolactoneA PHA derived from glucose. It has exfoliating and humectant properties and acts as a penetration enhancer for other ingredients. It has also been shown to assist in the treatment of acne and the prevention of photoaging.
Acetyl Glycyl Beta-Alanine
Est. %2
Function
Origin
Acetyl Glycyl Beta-Alanine
Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Lactic Acid
Est. %1.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Calcium Gluconate
Est. %0.3
Function
Origin
Calcium GluconateA white crystalline powder that can act as a humectant when dissolved into water. It is also a chelating agent.
Sodium Metabisulfite
Est. %0.3
Function
Origin
Sodium MetabisulfiteA preservative that is especially effective at preventing fungus and mold growth. It is normally combined with a strong bactericidal preservative in order to achieve broad-spectrum protection. Sodium metabisulfite is also used as an antioxidant.
Tetrapeptide-30
Est. %0.3
Function
Origin
Tetrapeptide-30
Hydroxyresveratrol
Est. %0.3
Function
Origin
Hydroxyresveratrol