iS Clinical Poly-Vitamin Serum

iS Clinical Poly-Vitamin Serum
3.2
/ 10
Moisturizing
5.8 Humectancy icon Humectancy
0.5 Occlusivity icon Occlusivity
4Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
$$$$

Review

Results you may expect from using iS Clinical Poly-Vitamin Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using iS Clinical Poly-Vitamin Serum:

  • Light moisturizing. It has a moisturizing rating of 3.2 out of 10.
  • Considerable anti-wrinkle efficacy: iS Clinical Poly-Vitamin Serum has an anti-wrinkle rating of 4.0 out of 10, indicating a moderate ability to reduce wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Lightly moisturizing: iS Clinical Poly-Vitamin Serum has a moisturizing rating of 3.2 out of 10.

Is it more humectant or occlusive? Rather humectant. It has a low occlusivity of 0.5 out of 10 and a moderate humectancy of 5.8 out of 10, primarily due to Sodium Hyaluronate (est. ≈1.5%), Saccharum Officinarum (Sugarcane) Extract (est. ≈1.4%) and Pantothenic Acid (est. ≈1.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical Poly-Vitamin Serum has a moderate anti-wrinkle rating of 4.0 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Retinol (est. ≈0.1%),
     the most effective non-prescription ingredient with well-proven efficacy to reduce wrinkles.
  • Niacinamide (est. ≈1.0%),
     one of the most effective and well-researched anti-wrinkle ingredients.
Among others, iS Clinical Poly-Vitamin Serum also contains Camellia Sinensis Leaf Extract, an ingredient marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Camellia Sinensis Leaf Extract provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that iS Clinical Poly-Vitamin Serum is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈1.5%), Saccharum Officinarum (Sugarcane) Extract (est. ≈1.4%), Niacinamide (est. ≈1.0%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
90
1.5
1.4
1
1
1
1
0.1
0.3
0.3
0.3
0.3
0.3
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Function:
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Ratings

All humectants
5.8
1.5
1.4
1
1
0.3
0.3
0.3
Benchmark
10
All occlusives
1.0
1.0
Benchmark
20
Moisturizing rating
3.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 5.8 10
5.8
1.5
1.4
1
1
0.3
0.3
0.3
Occlusivity All occlusives 1.0 20
0.5
1.0
Moisturizing rating
3.2
Ingredient Est. % Benchmark Humectancy
1.5
1.4
1
1
0.3
0.3
0.3
All humectants 5.8 10
5.8
All humectants
5.8
1.5
1.4
1
1
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1
All occlusives 1.0 20
0.5
All occlusives
1.0
1.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
6 /10 4 1 1.5
n/a
- 0.3 -
Total
4
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Niacinamide
1.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.4
1
1
0.3
0.3
All antioxidants 5.5 3 Rich in antioxidants
All antioxidants
5.5
Sodium Hyaluronate
1.5
Saccharum Officinarum (Sugarcane) Extract
1.4
Niacinamide
1
Tocopherol
1
Vaccinium Myrtillus Fruit Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1
0.3
All soothing 1.3 5 No
All soothing
1.3
1
0.3
Benchmark
5

Ingredients explained

Water
Est. %90
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Sodium Hyaluronate
Est. %1.5
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Saccharum Officinarum (Sugarcane) Extract
Est. %1.4
Function
Origin
An antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Zinc Sulfate
Est. %1
Function
Origin
Description is coming soon
Pantothenic Acid
Est. %1
Function
Origin
Also known as vitamin B5, this ingredient helps to restore healthy moisturization of the skin and is essential for good skin health. Due to poor stability and skin penetration, panthenol is usually preferred over pantothenic acid.
Niacinamide
Est. %1
Function
Origin

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Tocopherol
Est. %1
Function
Origin
Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.
Retinol
Est. %0.1
Function
Origin

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Lysine
Est. %0.3
Function
Origin
A humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It is slightly alkaline and helps to balance the product's pH. It may have a slightly fishy smell.
Glutamine
Est. %0.3
Function
Origin
A humectant moisturizing amino acid that, aside from attracting water to the skin’s surface, can also soothe allergic itching and reduce the signs of inflammation.
Vaccinium Myrtillus Fruit Extract
Est. %0.3
Function
Origin
An extract derived from the berries of the bilberry plant, sometimes called European blueberry. It is rich in antioxidant anthocyanins and astringent tannins.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.