According to CreamScan analysis, iS Clinical Hydra-Cool Serum is lightly moisturizing, with a moisturizing rating of 2.4 out of 10.
Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a moderate humectancy of 4.8 out of 10, due to the high content of Sodium Hyaluronate (est. ≈2.5%) and Pentylene Glycol (est. ≈2.3%).
This product, when used alone as a moisturizer, can provide light humectant hydration in a fast-absorbing formula without any occlusive ingredients. This could work for people with oily skin who need a basic level of hydration.
Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.
But it’s not limited to oily skin - since it contains a moderate amount of humectants, such a humectant add-on will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer.
Please refer to the Ratings section below for details of the moisturizing rating calculation.
According to CreamScan analysis, iS Clinical Hydra-Cool Serum has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.
Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.
We estimate that iS Clinical Hydra-Cool Serum is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈2.5%).
A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.
Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.
While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.
One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.
If you’re using iS Clinical Hydra-Cool Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.
If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.
Est. %
The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more | Ingredient | Origin | Functions | |
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85 | Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients. Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients. | Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. | Formula helper
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2.5 | Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties. Sodium Hyaluronate A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties. | Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) | Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. | |
2.4 | Calcium Pantothenate A vitamin B5 derivative that reduces static buildup on the skin. Calcium Pantothenate A vitamin B5 derivative that reduces static buildup on the skin. | Naturally occurring, These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring, These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. | Formula helper
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2.3 | Pentylene Glycol A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent. Pentylene Glycol A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent. | Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria. Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria. | Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Preservative, Preservatives prevent the growth of bacteria and fungi in a product. Preservative, Preservatives prevent the growth of bacteria and fungi in a product. Formula helper
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2 | Menthol A volatile compound isolated from peppermint oil. It causes a cooling sensation on the skin that can be very soothing. Menthol can also act as a topical painkiller. In more sensitive individuals, however, it may cause skin irritation or an allergy. Menthol A volatile compound isolated from peppermint oil. It causes a cooling sensation on the skin that can be very soothing. Menthol can also act as a topical painkiller. In more sensitive individuals, however, it may cause skin irritation or an allergy. | Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. | Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Flavor, Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Flavor, Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Refreshing, Refreshing ingredients leave the skin feeling refreshed and 'awake'. Refreshing, Refreshing ingredients leave the skin feeling refreshed and 'awake'. Formula helper
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1 | Phenoxyethanol The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless. Phenoxyethanol The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless. | Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. | Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product. | |
1 | Asiaticoside A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy. Asiaticoside A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy. | Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. | Antioxidant, Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant, Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. | |
1 | | Fungi Fungi is a unique kingdom of organisms including single-cell yeasts, molds, and mushrooms. They are a rich source of cosmetic ingredients such as mushroom extracts, oils, and powders. Fungi Fungi is a unique kingdom of organisms including single-cell yeasts, molds, and mushrooms. They are a rich source of cosmetic ingredients such as mushroom extracts, oils, and powders. | ||
0.3 | Asiatic Acid A compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process. Asiatic Acid A compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process. | Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. | Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Formula helper
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0.3 | Madecassic Acid An isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns. Madecassic Acid An isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns. | Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. | Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. | |
0.3 | Blue 1 (CI 42090) A synthetic dye commonly known as Brilliant Blue FCF that produces rich blue colors for various cosmetic uses. FD&C Blue #1 can also be found in foods, medications, and dietary supplements, as it is considered non-toxic and safe for use. Blue 1 (CI 42090) A synthetic dye commonly known as Brilliant Blue FCF that produces rich blue colors for various cosmetic uses. FD&C Blue #1 can also be found in foods, medications, and dietary supplements, as it is considered non-toxic and safe for use. | Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. | Colorant Colorants give color to skincare products. Colorant Colorants give color to skincare products. | |
85 Water Function: Formula helper Formula helper
Formula helper Formula helper
Origin: Naturally occurring Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. |
2.5 Sodium Hyaluronate Function: Moisturizing (Humectant), Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Origin: Biotech, Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Animal Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) |
2.4 Calcium Pantothenate Function: Formula helper Formula helper
Formula helper Formula helper
Origin: Naturally occurring, Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring, Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. |
2.3 Pentylene Glycol Function: Moisturizing (Humectant), Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Preservative, Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative, Preservative Preservatives prevent the growth of bacteria and fungi in a product. Formula helper Formula helper
Formula helper Formula helper
Origin: Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Petroleum Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria. Petroleum Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria. |
2 Menthol Function: Soothing, Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Fragrance, Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Flavor, Flavor Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Flavor, Flavor Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Refreshing, Refreshing Refreshing ingredients leave the skin feeling refreshed and 'awake'. Refreshing, Refreshing Refreshing ingredients leave the skin feeling refreshed and 'awake'. Formula helper Formula helper
Formula helper Formula helper
Origin: Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. |
1 Phenoxyethanol Function: Antimicrobial, Antimicrobial Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobial Antimicrobials prevent the growth of harmful microorganisms on the skin. Preservative Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservative Preservatives prevent the growth of bacteria and fungi in a product. Origin: Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. |
1 Asiaticoside Function: Antioxidant, Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant, Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Anti-Wrinkle, Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle, Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Fragrance Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Origin: Botanical Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. |
1 Polyporus Umbellatus (Mushroom) Extract Function: Origin: Fungi Fungi Fungi is a unique kingdom of organisms including single-cell yeasts, molds, and mushrooms. They are a rich source of cosmetic ingredients such as mushroom extracts, oils, and powders. Fungi Fungi Fungi is a unique kingdom of organisms including single-cell yeasts, molds, and mushrooms. They are a rich source of cosmetic ingredients such as mushroom extracts, oils, and powders. |
0.3 Asiatic Acid Function: Anti-Wrinkle, Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle, Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Formula helper Formula helper
Formula helper Formula helper
Origin: Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. |
0.3 Madecassic Acid Function: Anti-Wrinkle Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Origin: Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. |
0.3 Blue 1 (CI 42090) Function: Colorant Colorant Colorants give color to skincare products. Colorant Colorant Colorants give color to skincare products. Origin: Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. |