Darphin INTRAL Redness Relief Soothing Serum Review

Darphin INTRAL Redness Relief Soothing Serum
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Ingredients

Darphin INTRAL Redness Relief Soothing Serum Ingredients

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Full Ingredient List (INCI):

Water, Butylene Glycol, Glycerin, Chamomilla Recutita (Matricaria) Flower Extract, Paeonia Suffruticosa Root Extract, Alteromonas Ferment Extract, Crataegus Monogyna Flower Extract, Panthenol, Glycosaminoglycans, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Yeast Extract, PEG-40 Hydrogenated Castor Oil, Cellulose Gum, Glycereth-26, Fragrance, Citric Acid, Xanthan Gum, Disodium EDTA, Chlorphenesin, Sodium Benzoate, Phenoxyethanol, Red 4 (CI 14700), Ext. Violet 2 (CI 60730), Yellow 5 (CI 19140), Red 33 (CI 17200), Blue 1 (CI 42090)
Review

Does Darphin INTRAL Redness Relief Soothing Serum Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Darphin INTRAL Redness Relief Soothing Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Soothing: Darphin INTRAL Redness Relief Soothing Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Darphin INTRAL Redness Relief Soothing Serum

 
These are the key benefits you can expect from using Darphin INTRAL Redness Relief Soothing Serum:
 

🔵 Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Darphin INTRAL Redness Relief Soothing Serum is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%) and Glycerin (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Darphin INTRAL Redness Relief Soothing Serum is rich (> 3%) in antioxidants, specifically Chamomilla Recutita (Matricaria) Flower Extract (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Darphin INTRAL Redness Relief Soothing Serum is rich (> 5%) in soothing ingredients, particularly Chamomilla Recutita (Matricaria) Flower Extract (est. ≈3.0%) and Paeonia Suffruticosa Root Extract (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Darphin INTRAL Redness Relief Soothing Serum

 
CreamScan identified a few things to consider before adding Darphin INTRAL Redness Relief Soothing Serum to your skincare routine:
 

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Darphin INTRAL Redness Relief Soothing Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

⚠️ Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Darphin INTRAL Redness Relief Soothing Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Alteromonas Ferment Extract, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Alteromonas Ferment Extract provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically rule out the possibility that Alteromonas Ferment Extract may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.

Therefore, this ingredient does not generate the anti-wrinkle rating.

📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Darphin INTRAL Redness Relief Soothing Serum

 
Here’s an overview of the pros and cons of Darphin INTRAL Redness Relief Soothing Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients like Chamomilla Recutita (Matricaria) Flower Extract and Paeonia Suffruticosa Root Extract
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
⚠️ Questionable anti-wrinkle efficacy
   

Summary: Darphin INTRAL Redness Relief Soothing Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Darphin INTRAL Redness Relief Soothing Serum
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
Rich in antioxidants, Darphin INTRAL Redness Relief Soothing Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
That said, there are some things about Darphin INTRAL Redness Relief Soothing Serum worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
If one of your main reasons for considering Darphin INTRAL Redness Relief Soothing Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, its anti-wrinkle efficacy is questionable. None of the ingredients in this product provide substantial evidence of their anti-wrinkle efficacy according to CreamScan Research Evaluation Standards.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Paeonia Suffruticosa Root Extract
Function:
Origin:
Alteromonas Ferment Extract
Function:
Origin:
Crataegus Monogyna Flower Extract
Function:
Origin:
Panthenol
Function:
Origin:
Glycosaminoglycans
Function:
Origin:
Polygonum Cuspidatum Root Extract
Function:
Origin:
Saccharomyces Lysate Extract
Function:
Origin:
Yeast Extract
Function:
Origin:
PEG-40 Hydrogenated Castor Oil
Function:
Origin:
Cellulose Gum
Function:
Origin:
Glycereth-26
Function:
Origin:
Fragrance
Function:
Origin:
Citric Acid
Function:
Origin:
Xanthan Gum
Function:
Origin:
Disodium EDTA
Function:
Origin:
Chlorphenesin
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Red 4 (CI 14700)
Function:
Origin:
Ext. Violet 2 (CI 60730)
Function:
Origin:
Yellow 5 (CI 19140)
Function:
Origin:
Red 33 (CI 17200)
Function:
Origin:
Blue 1 (CI 42090)
Function:
Origin:

Ratings

All humectants
11.9
6
4
1
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 11.9 10
10.0
6
4
1
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
1
0.3
0.3
0.3
All humectants 11.9 10
10
All humectants
11.9
6
4
1
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 1.5 -
Total
0
Alteromonas Ferment Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
3
1.3
0.3
All antioxidants 4.6 3 Rich in antioxidants
All antioxidants
4.6
Chamomilla Recutita (Matricaria) Flower Extract
3
Crataegus Monogyna Flower Extract
1.3
Polygonum Cuspidatum Root Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
2
1.5
1
0.3
All soothing 7.8 5 Rich in soothing
All soothing
7.8
3
2
1.5
1
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Chamomilla Recutita (Matricaria) Flower Extract
Est. %3
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Paeonia Suffruticosa Root Extract
Est. %2
Function
Origin
Paeonia Suffruticosa Root ExtractA soothing extract obtained from a hybrid species of tree peony that contains various active compounds such as astringent tannins, terpenes, and paeonols.
Alteromonas Ferment Extract
Est. %1.5
Function
Origin
Alteromonas Ferment ExtractAn (allegedly) anti-wrinkle mixture of exopolysaccharides from marine microorganisms.
Crataegus Monogyna Flower Extract
Est. %1.3
Function
Origin
Crataegus Monogyna Flower ExtractAn extract obtained from the flowers of the hawthorn bush. It has a high content of astringent and antioxidant tannins and flavonoids.
Panthenol
Est. %1
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Glycosaminoglycans
Est. %0.3
Function
Origin
GlycosaminoglycansA blanket term used for the structural polysaccharides of the skin, such as hyaluronic acid and chondroitin. They add to a skincare product's film-forming and water-binding properties.
Polygonum Cuspidatum Root Extract
Est. %0.3
Function
Origin
Polygonum Cuspidatum Root ExtractAn extract from the roots of the Japanese knotweed, a plant from East Asia that has spread around the world as an invasive plant. It contains various antioxidant, anti-inflammatory, and potentially anti-pigment (more tests are necessary) phytochemicals.
Saccharomyces Lysate Extract
Est. %0.3
Function
Origin
Saccharomyces Lysate ExtractA mixture of yeast cell fragments with humectant moisturizing properties. It contains many beneficial compounds, including a wound healing polysaccharide called beta-glucan, peptides, and various minerals and vitamins.
Yeast Extract
Est. %0.3
Function
Origin
Yeast ExtractAlso labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
PEG-40 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
PEG-40 Hydrogenated Castor OilA castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
Cellulose Gum
Est. %0.3
Function
Origin
Cellulose GumA polymer that is derived from its namesake, cellulose, which is plant-based. It has many formula-helper benefits, including thickening and product stabilization.
Glycereth-26
Est. %0.3
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Red 4 (CI 14700)
Est. %0.3
Function
Origin
Red 4 (CI 14700)A synthetic dye that is also known as FD&C Red No. 4. This colorant produces a warm red hue that has an orange or yellow undertone.
Ext. Violet 2 (CI 60730)
Est. %0.3
Function
Origin
Ext. Violet 2 (CI 60730)
Yellow 5 (CI 19140)
Est. %0.3
Function
Origin
Yellow 5 (CI 19140)A bright yellow colorant that is often also listed as FD&C Yellow 5.
Red 33 (CI 17200)
Est. %0.3
Function
Origin
Red 33 (CI 17200)Also known as D&C Red 33 or Acid Red 33, this ingredient is a synthetic azo used to color skincare products. It produces a cool red hue, with undertones of blue that lead to a hint of purple.
Blue 1 (CI 42090)
Est. %0.3
Function
Origin
Blue 1 (CI 42090)A synthetic dye commonly known as Brilliant Blue FCF that produces rich blue colors for various cosmetic uses. FD&C Blue #1 can also be found in foods, medications, and dietary supplements, as it is considered non-toxic and safe for use.