Trehalose

A sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Moisturizing
Other functions
Origin
Trehalose

Overview

Trehalose is a sweet-tasting saccharide consisting of two glucose molecules (a.k.a. disaccharide, similar to sucrose or lactose).

It can be found in various yeasts and fungi and is manufactured from starch for cosmetic purposes. It is mainly used for its humectant properties in skincare products (i.e., its ability to attract and bind water to the skin’s surface), as well as its ability to protect the top layer of the skin from drying out.

It is also used as a flavoring agent due to its sweet taste. When compared to sucrose, it is more stable in different pHs and temperatures, less sticky, and holds water better - which makes it one of the most used sugars in cosmetic formulations. It is also able to mask the unpleasant odor of other ingredients.

The latest dermatologic publications are currently exploring the possibility of using Trehalose as an anti-acne ingredient because it seems to (very simply put) slow down the clogging of the sebaceous glands by regulating the speed at which skin cells divide and peel off.

For this effect to work, however, the ingredient needs to be packed into a special skin delivery system called liposomes.

Science

1
Fiume, M. et al. (2019). Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics. International Journal of Toxicology, Vol. 38(Supplement 1) 5S-38S
2
Ohtake, S., & Wang, Y. J. (2011). Trehalose: current use and future applications. Journal of pharmaceutical sciences, 100(6), 2020–2053.
3
Fabbrocini, G., Capasso, C., Donnarumma, M., Cantelli, M., Le Maître, M., Monfrecola, G., & Emanuele, E. (2017). A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy. Journal of cosmetic dermatology, 16(4), 480–484.