sh-Polypeptide-8 is a single chain synthetic human peptide, produced by fermentation in E.Coli. The starting gene is a synthesized copy of the human gene which codes for Platelet Derived Growth Factor used as such or adapted to the production host. It contains a maximum of 211 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.