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Creamscan anti-wrinkle rating is a weighted result of 2 parts:
1
Reported Efficacy: This measures the ingredient's
ability to reduce wrinkles, confirmed by a double-blind, vehicle-controlled, randomized study. We compare the results reported in the study against a gold standard anti-wrinkle
benchmark, 0.05% Tretinoin, to calculate a 0-10 efficacy score for the reviewed
ingredient.
2
Strength of Evidence: This reflects how thoroughly
an ingredient has been researched. While there are many studies on cosmetic ingredients,
very few are robust, vehicle-controlled clinical trials on humans.
Each study meeting
CreamScan Research Evaluation Standards
earns the ingredient 5 points. An ingredient with just one qualifying study receives
a score of 5 out of 10 for Strength of Evidence. To achieve a perfect score of 10 out
of 10, an ingredient must have at least two studies confirming its efficacy from different
research teams.