A short, synthetically made peptide similar to elastin fragments. It works as a signal peptide, stimulating the growth of skin cells and facilitating skin repair. It has been tested mostly in test-tube experiments so far.
Palmitoyl Hexapeptide-12 is a short peptide consisting of six amino acids: Val-Gly-Val-Ala-Pro-Gly, with palmitic acid on one end to enhance its lipid solubility. This amino acid sequence can be found many times in elastin, one of the main structural proteins of our skin.
Hexapeptide-12 functions as a signal molecule in the dermis, stimulating the growth of fibroblasts, as well as the restructuring and repair of the skin.
The manufacturer trademarked this ingredient under the name Biopeptide-EL as an anti-aging and anti-wrinkle ingredient. So far, this claim has been supported by two test-tube experiments and by a small clinical trial by the manufacturer with a 4% cream.