An amino acid that is claimed to be able to restore the adipose tissue in the skin, thereby making it look plumper and filled out. This has not been proven by studies as of yet.
Ornithine is a non-proteinogenic amino acid (meaning that it does not serve as a building block of proteins) that has a function in nitrogen metabolism.
There is very little research concerning the effects of ornithine on the skin, and as a small, water-soluble molecule, it is not readily absorbed.
It was recently incorporated into a trademarked preparation called Adipofillâ„¢, which consists of ornithine encapsulated into a special delivery system.
The manufacturer's tests claim that it restores the adipose tissue in the skin, resulting in a plumper, more filled-out look and an improvement in deep wrinkles and sagging skin. They claim that this is due to ornithine’s ability to revive atrophied fatty tissue and to increase the number and the activity of fatty cells (adipocytes).
Unfortunately, there are no other independent studies to confirm this claim.