Leontopodium Alpinum Callus Culture Extract

Plant cells of the Edelweiss flower are grown into a so-called callus culture in order to extract active compounds of the plant. One of the compounds is leontopodic acid, which has antioxidant, antibacterial, and soothing effects.
Moisturizing
Antioxidant
Soothing
Other functions
Origin
Leontopodium Alpinum Callus Culture Extract

Overview

Leontopodium alpinum callus culture extract is a unique ingredient with very promising anti-aging properties, but with a complicated method of production. So let’s break it down.

Leontopodium alpinum, or Edelweiss, is a beautiful and rare alpine plant that grows in the high altitudes of the Alps and Carpathian regions of Europe. Its leaves and flowers are covered in thick, white fuzzy hairs that protect the plant from harsh weather and UV light. It is a symbol of alpinism and mountain hiking. The plant is relatively rare, although it can be cultivated to an extent.

Alternatively, the cells can be taken from the plant and grown in a lab into a so-called callus culture, which looks more or less like green goo. However, this disordered bunch of plant cells can contain the same active compounds as the source plant. In this case, the scientists were aiming for leontopodic acid, which seems to be the compound responsible for the antioxidant, antibacterial, and anti-inflammatory properties.

Leontopodium alpinum callus culture extract was recently tested in a study in both test-tubes and on volunteers. It seems to be an effective anti-aging ingredient since it reduced the appearance of wrinkles and fine lines and improved skin elasticity and thickness after 2 and 4 weeks of use. The test-tube experiment highlighted its antioxidant, anti-inflammatory, and humectant moisturizing properties.

Science

1
Cho, W. K., et al. (2020). Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling. Genes, 11(2), 230. https://doi.org/10.3390/genes11020230
2
Daniela, L., Alla, P., Maurelli, R., Elena, D., Giovanna, P., Vladimir, K., Roberto, D. T., Chiara, d., Saveria, P., & Liudmila, K. (2012). Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells. Mediators of inflammation, 2012, 498373. https://doi.org/10.1155/2012/498373