A biotechnological mixture of various skin growth factors. It is thought to be able to stimulate the growth and regeneration of all skin layers, although the use of growth factors in skincare is still controversial.
Moisturizing
Humectant
Moisturizing (Humectant)
Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
Humectant
Moisturizing (Humectant)
Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
Origin
Biotech,
Biotech
The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.
Biotech,
Biotech
The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.
Human
Human
These are ingredients mainly derived from human stem cells and human cell cultures. Their sources are little samples of human skin, fat, bone marrow, or umbilical blood.
Human
Human
These are ingredients mainly derived from human stem cells and human cell cultures. Their sources are little samples of human skin, fat, bone marrow, or umbilical blood.
Human fibroblast conditioned media is a biotechnological ingredient – a mixture of various molecules and growth factors taken from a laboratory-made culture medium that was used for the growth of human skin cells called fibroblasts. During their life, these skin cells produced various proteins, peptides, and other molecules which they released into the surrounding liquid.
The main active in this ingredient are the growth factors – proteins that stimulate the growth and regeneration of all skin layers.
There is currently a trend of experimenting with growth factors for the promotion of skin regeneration and anti-aging effects.
There are some controversies – mainly the ethical issue of using human cells for the production of growth factors, general safety concerns regarding their widespread use in skincare, and more.
So far there have been no unfortunate incidents with these anti-aging ingredients and the reported effects are also very promising, so let's hope that it stays that way.
Science
1
Hur, W., Lee, H.Y., Min, H.S. et al. Regeneration of full-thickness skin defects by differentiated adipose-derived stem cells into fibroblast-like cells by fibroblast-conditioned medium. Stem Cell Res Ther 8, 92 (2017).
2
Albert J. T. Millis, Marian Hoyle, Brenda Field (1977). Human fibroblast conditioned media contains growth‐promoting activities for low density cells. Journal of Cellular Physiology, Volume 93, Issue 1.
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Humectant
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