An antioxidant and soothing flavonoid compound that is found in abundance in citrus fruit peels. It has been chemically modified for better absorption.
Antioxidant
Antioxidant
Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging.
Antioxidant
Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging.
Soothing
Soothing
Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics.
Soothing
Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics.
Origin
Synthetic
Synthetic
All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.
Synthetic
Synthetic
All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.
Hesperidin methyl chalcone is an antioxidant and anti-inflammatory, chemically modified, plant-based bioactive compound.
The original molecule, hesperidin, belongs to the class of flavonoids and can be found in large quantities in the peels of citrus fruits. Flavonoids are notoriously difficult to use in pill form because they do not get properly absorbed from the gastrointestinal tract – which is why they are sometimes chemically modified for better absorption and stability.
Hesperidin methyl chalcone is made by adding one methyl group to a hesperidin molecule, while also opening one of its cycles. It is used in pills against capillary fragility and chronic venous insufficiency.
In skincare, there have been experiments on animals and in test tubes that show its potential as an antioxidant and anti-inflammatory ingredient for the treatment of sun-damaged skin, but it has not been proven on living humans as of yet.
The anti-redness effect was tested as part of a bigger mixture of active compounds and extracts in the treatment of rosacea.
Science
1
Martinez, R. M., et al. (2015). Hesperidin methyl chalcone inhibits oxidative stress and inflammation in a mouse model of ultraviolet B irradiation-induced skin damage. Journal of Photochemistry and Photobiology B: Biology, 148, 145–153.
2
Hernandez-Pigeon, H., et al. (2017). Effects of TRP-regulin, pongamia oil and hesperidin methyl chalcone on anti-redness treatment. Journal of Investigative Dermatology, 137(10), B8.
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