Creatine

An amino acid-like compound that regulates cellular energy metabolism. It is used in skincare to moisturize and bind water to the skin and can also improve skin firmness when combined with folic acid.
Moisturizing
Origin
Creatine

Overview

Creatine is a compound naturally found in all the cells of the human body. It is technically an amino acid but not the one used to build proteins. Instead, it has a wide range of responsibilities in cell energy metabolism.

In skincare, creatine is used as a humectant moisturizing ingredient, able to bind and retain water. There was a single study on 12 female volunteers that reported improved skin firmness after the application of a skin cream containing creatine in combination with folic acid. That is a promising result, but we cannot be sure if it was due to the creatine or the folic acid.

Science

1
Fischer, F., et al. (2011). Folic acid and creatine improve the firmness of human skin in vivo. Journal of Cosmetic Dermatology, 10(1), 15–23.