A powerful bioactive compound designed to soothe irritated, burning, and itchy skin. The effectiveness of its soothing properties has been proven by clinical trials and it is often combined with other soothing ingredients.
Soothing
Soothing
Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics.
Soothing
Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics.
Other functions
Fragrance
Fragrance
Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients.
Fragrance
Fragrance
Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients.
4-t-butylcyclohexanol is a molecule that was developed to provide a soothing sensation to irritated and itchy skin.
It has the ability to bind to and inhibit TRPV1 thermoreceptors in the skin, which are responsible for burning sensations, and has been successfully tested in various human trials. One study reported that it inhibited the burning sensation caused by capsaicin (the burning chemical from chilli peppers) and, in a cream formulation, helped with burning and itching dermatitis around the mouth and eyes.
The results of this study are very promising – after 8 weeks the itching, burning, redness, and dryness of the skin were significantly reduced, with 48 test subjects reporting an increased quality of life and general satisfaction with the cream.
In many other studies, it was combined with other active ingredients for the treatment of rosacea, eczema, and atopic dermatitis, making it a scientifically proven soothing ingredient.
Science
1
Kueper, T., et al. (2010). Inhibition of TRPV1 for the treatment of sensitive skin. Experimental dermatology, 19(11), 980–986.
2
Srour, J., et al. (2020). Efficacy of a skin care cream with TRPV1 inhibitor 4-t-butylcyclohexanol in the topical therapy of perioral dermatitis. Journal of cosmetic dermatology, 19(6), 1409–1414.
'%20fill='black'/%3e%3c/svg%3e)
